Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7629595 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 36 Pages |
Abstract
- This is the first report for the thorough studies of the pharmacokinetics and tissue distribution profiles of DAT-230 in rats.
- The plasma sample preparation procedure was one-step precipitation of proteins.
- The mean pharmacokinetic parameters of t1/2 and AUC0-12 were 1.1 ± 0.4 h and 861.0 ± 281.2 ng h/mL, respectively.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jingya Tang, Chungang Zhang, Jun Sun, Longshan Zhao, Weige Zhang, Zhenzhen Liu, Lu Sun, Xiaohui Chen,