| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629615 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 9 Pages |
Abstract
- We developed an LC-MS/MS assay to quantify the active 5-FU nucleotides in PBMCs.
- Release from the cell matrix and endogenous interference were carefully optimized.
- First time 5-FU nucleotides were quantified in patient cells without radiolabel.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Ellen J.B. Derissen, Michel J.X. Hillebrand, Hilde Rosing, Jan H.M. Schellens, Jos H. Beijnen,