| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629625 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 10 Pages |
Abstract
- Methyl salicylate-2-O-β-D-lactoside and the metabolite of salicylic acid could be quantified by UPLC-MS/MS method in biological samples.
- Evaluate the pharmacokinetic, distribution and excretion of methyl salicylate-2-O-β-d-lactoside in rats.
- Hydrolysed, sulfated and glucuronidated products are the main metabolites.
Keywords
CmaxQ-TOF-MSMSLtmaxUPLCESIAUCLC–MS/MSinternal standardSalicylic acidmaximum concentrationtime to maximum concentrationTandem mass spectrometryQuadrupole-time-of-flight mass spectrometryliquid chromatography-mass spectrometry/mass spectrometrypharmacokineticMetabolitesultra performance liquid chromatographyelectrospray ionization
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Dan Zhang, Chao Huang, Wenyu Xin, Xiaowei Ma, Weiku Zhang, Tiantai Zhang, Guanhua Du,