| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629631 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- Different enzyme sources were compared on their ability to form GSH conjugates.
- Incubations with microsomes, S9 fraction, hepatocytes and HepaRG cells.
- Test pattern of 10 diverse test compounds.
- Incubations with subfractions produced more GSH-conjugates than cell-based systems.
- Different major GSH conjugates in subfractions and cell-based systems.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Toni Lassila, Timo Rousu, Sampo Mattila, Christophe Chesné, Olavi Pelkonen, Miia Turpeinen, Ari Tolonen,