| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629672 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 41 Pages |
Abstract
- A new chiral CE method was developed to analyze zopiclone and its main metabolites.
- DLLME showed to be a useful technique to extract the analytes from culture medium.
- The developed method is the fastest one for the chiral analysis of these analytes.
- The Cunninghamella fungi metabolized the drug zopiclone, enantioselectively.
- The fungus C. elegans preferentially afforded the metabolite (S)-N-desmethylzopiclone.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Nayara Cristina Perez de Albuquerque, Cristiane Masetto de Gaitani, Anderson Rodrigo Moraes de Oliveira,