| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629693 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 29 Pages |
Abstract
ⶠSensitive LC-MS/MS methods for pregabalin determination in DBS and DPS. ⶠDerivatization of pregabalin with n-propyl chloroformate/n-propanol combination. ⶠDBS concentration correction was suggested, due to hematocrit effect. ⶠThe validated methods were applied to samples obtained from epileptic patients. ⶠCorrelation of DBS and DPS levels for estimation of pregabalin distribution into RBC.
Related Topics
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Authors
NaÄa KostiÄ, Yannis Dotsikas, NebojÅ¡a JoviÄ, Galina StevanoviÄ, AnÄelija MalenoviÄ, Mirjana Medenica,