Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7629706 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- Three polymorphic forms of the immunomodulatory drug, fingolimod hydrochloride (FTY 720), are highly temperature dependent.
- The reversible single-crystal to single-crystal transformations were studied using different analytical techniques (XRD, DSC, and Raman).
- Form I is stable at ambient condition, while II and III could change to I when appropriate temperature applied.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jian-Rong Wang, Sha Li, Bingqing Zhu, Xuefeng Mei,