| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629821 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- Quantitation of BMS-791325 and active metabolite in plasma and urine by LC-MS/MS.
- The validation results demonstrate the method is accurate, precise, and reproducible.
- Coadministered famotidine and ritonavir did not affect the LC-MS/MS method.
- Crossvalidation after method transfers demonstrated method equivalency.
- The plasma method was used for pharmacokinetic evaluation in many clinical studies.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Hao Jiang, Roger Demers, Hamza Kandoussi, Richard Burrell, Timothy Eley, Pathanjali Kadiyala, Laura Cojocaru, Chanda Baker, John Ryan, Anne-Françoise Aubry, Mark E. Arnold, Jianing Zeng,