Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7629943 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 31 Pages |
Abstract
- Highly selective method for the determination of ibrutinib, PCI-45227 and lenalidomide in plasma.
- This is the first LC-MS/MS-based method for simultaneous determination of ibrutinib, PCI-45227 and lenalidomide in plasma.
- Plasma sample clean-up involves a simple liquid-liquid extraction procedure.
- The developed LC-MS/MS based method was applied successfully for pharmacokinetic study.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Sridhar Veeraraghavan, Srikant Viswanadha, Satheeshmanikandan Thappali, Babu Govindarajulu, Swaroopkumar Vakkalanka, Manivannan Rangasamy,