Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7629948 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- IR spectroscopy showed absence of chemical interaction between excipients and drug.
- In thermal analysis physical interaction between excipients and drug was identified.
- Some excipients promoted but some reduced stability of the API unstable polymorph.
- Phase transition rate of API depended on the type and the amount of excipient added.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
KristÄ«ne KrÅ«kle-BÄrziÅa, Andris ActiÅÅ¡,