| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630025 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 8 Pages |
Abstract
- We converted sertraline hydrochloride salt into the free base.
- Sertraline base and β-CD form a 1:1 inclusion complex in the solid-state.
- Sertraline base-β-CD complex shows high apparent stability constant.
- Sertraline base-β-CD complex shows the conformational changes from the constituent.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Noriko Ogawa, Takuro Hashimoto, Takayuki Furuishi, Hiromasa Nagase, Tomohiro Endo, Hiromitsu Yamamoto, Yoshiaki Kawashima, Haruhisa Ueda,