| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630171 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 38 Pages |
Abstract
- Simultaneous quantitation of three novel HCV drugs in human plasma by LC-MS/MS.
- The validation results demonstrate the method is accurate, precise, and reproducible.
- Cross-validation results demonstrated method equivalency with those for single drug.
- The plasma method was used for pharmacokinetic assessment in many clinical studies.
- Multiplexed LC-MS/MS method is time- and cost-effective, and maintains high performance in sample analysis.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Hao Jiang, Hamza Kandoussi, Jianing Zeng, Jian Wang, Roger Demers, Timothy Eley, Bing He, Richard Burrell, John Easter, Pathanjali Kadiyala, Janice Pursley, Laura Cojocaru, Chanda Baker, John Ryan, Anne-Françoise Aubry, Mark E. Arnold,