| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630292 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 6 Pages |
Abstract
- Fully FDA validated method for tacrolimus quantification in PBMC samples.
- One of the first methods using UPLC-MS/MS technology coupled automated on-line SPE.
- Easy to use method in clinical routine.
Keywords
TACESI+TDMMCVULOQQCsUPLCOSMSPECPTRSDFK-506PBMCLLOQMS/MSSTDsStandardsSolid phase extractionrelative standard deviationTacrolimustandem massMassupper limit of quantificationlower limit of quantificationIntracellularLLODPeripheral blood mononuclear cellliquidlower limit of detectiontherapeutic drug monitoringultra performance liquid chromatographyhigh performance liquid chromatographyHPLCquality controlsPositive electrospray ionization
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Debora Pensi, Amedeo De Nicolò, Michele Pinon, Pier Luigi Calvo, Antonello Nonnato, Andrea Brunati, Giovanni Di Perri, Antonio D'Avolio,