| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630530 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 10 Pages |
Abstract
- The formation of genuine ternary complexes was demonstrated by NMR studies, IR-spectroscopy, DSC, TG and DRX.
- A higher drug amorphization was found for the lyophilized ternary complexes than the binary ones.
- A significant 29-fold increase in solubility was obtained for SMR in the complex with MβCD and MEG in water.
- The ternary complex with HPβCD provided significant enhancement effects on the release of SMR.
- The ternary complexes with βCD and MβCD produced additional retention effects on the release of SMR.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Carolina Aloisio, Anselmo Gomes de Oliveira, Marcela Longhi,