| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630554 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 6 Pages |
Abstract
- New LC-MS method for analysis of palmatine and its metabolites was developed.
- Biotransformation of palmatine in human hepatocytes was examined for the first time.
- Phase I and phase II metabolites of palmatine were analyzed.
- CYP2D6 and to a lesser extent CYP1A2 metabolize palmatine in vitro.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jiri Vrba, Barbora Papouskova, Michaela Pyszkova, Martina Zatloukalova, Karel Lemr, Jitka Ulrichova, Jan Vacek,