Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7630571 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- A UPLC-MS/MS method was developed to determine HZ08 in rat plasma and tissues.
- The total analysis time was 4.0Â min.
- The method was applied to pharmacokinetic study of HZ08 in rats.
- HZ08 had linear pharmacokinetic properties with a rapid elimination phase.
- The major distribution tissues of HZ08 in rats were lung, spleen and liver.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Fang Yan, Miaomiao Sun, Taijun Hang, Jing Sun, Xia Zhou, Xin Deng, Liang Ge, Hai Qian, Ding Ya, Wenlong Huang,