| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630597 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 7 Pages |
Abstract
- LC method with chaotropic additives is developed following the QbD principles.
- Different analytes susceptibility to chaotropic salts effects influenced separation selectivity.
- D-optimal design enabled simultaneous examination of categorical and numerical factors.
- Two ways for the achievement of quality assurance are performed and compared.
- Propagation of error originating from the model coefficients' calculation is more strict approach.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Ana VemiÄ, Tijana RakiÄ, AnÄelija MalenoviÄ, Mirjana Medenica,