Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7630610 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 35 Pages |
Abstract
- Identified a total of 7 hydrolytic and isomeric N-oxides degradants of vilazodone.
- Comprehensive characterization of all degradants using online UPLC-QTOF-MS/MS.
- Demonstrated an application of APCI-MS to characterize isomeric N-oxides degradants.
- Mechanistic explanation of vilazodone degradation demonstrated.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Pradipbhai D. Kalariya, M.V.N. Kumar Talluri, Prinesh N. Patel, R. Srinivas,