| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630612 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 32 Pages |
Abstract
- Comprehensive validation of a LC-MS/MS assay for flupirtine, D-13223 in human serum, urine and feces (higher sensitivity).
- First validated LC-MS/MS assay to quantify two mercapturic acid derivates of flupirtine (M-424, M-466) in human urine.
- Application of these two methods to characterize the pharmacokinetics of FLU, D-13223, M-424 and M-466 in humans.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Eberhard Scheuch, Karen Methling, Patrick J. Bednarski, Stefan Oswald, Werner Siegmund,