| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630626 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 11 Pages |
Abstract
- Direct infusion mass spectrometry allows a comprehensive brain metabolomic analysis.
- The APP/PS1 mice exhibited an abnormal neurochemical profile compared to controls.
- These failures affected hippocampus, cortex, cerebellum and olfactory bulbs.
- Pathway analysis revealed multiple significant impairments in brain metabolism.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Raúl González-DomÃnguez, Tamara GarcÃa-Barrera, Javier Vitorica, José Luis Gómez-Ariza,