Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7630710 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 12 Pages |
Abstract
- We prepared 4 polymorphs of ampicillin: monohydrate, trihydrate, forms I and II.
- The four forms have been identified by characteristic FT-IR and Raman bands.
- DFT results on ampicillin zwitterion allowed assignment of IR and Raman bands.
- XRPD and thermal analysis differentiated the four polymorphs.
- After two years, no transformation/degradation of the polymorphs was evidenced.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
C. Baraldi, A. Tinti, S. Ottani, M.C. Gamberini,