| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630749 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 6 Pages |
Abstract
- Iso-fludelone (KOS-1803) is a synthetic third generation epothilone in phase I trials.
- An LC-MS/MS assay from 0.1 to 300Â ng/mL in 0.2Â mL plasma was validated and applied.
- This assay is currently utilized to quantitate iso-fludelone in clinical samples.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Susan M. Christner, Robert A. Parise, Erica D. Levine, Naiyer A. Rizvi, Mrinal M. Gounder, Jan H. Beumer,