Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7630754 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 7 Pages |
Abstract
- First LC-MS/MS method for the determination of clodronate in plasma.
- Comprehensive method validation according to current bioanalytical guidelines.
- Higher sensitivity compared to previously published methods (factor 2-60).
- Application of the method to monitor plasma concentration-time profiles in humans.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Mahmoud Hasan, Gitta Schumacher, Anne Seekamp, Tobias Taedken, Werner Siegmund, Stefan Oswald,