| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630756 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 8 Pages |
Abstract
- Novel derivatization for the rapid LC/MS quantification of neurotransmitters.
- Enable simultaneous quantization of amino acids in brain microdialysis samples.
- LOQ was single digit nM with linear dynamic a range up to 1000Â nM and coefficient >0.990.
- This method applied to brain microdialysis study in tetrodotoxin (TTX) treated rat.
- TTX inhibition of synaptic GABA, glutamate and glycine release was quantified.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Minli Zhang, Chengwei Fang, Gennady Smagin,