Identification of ɛ-caprolactam, melamine and urea in polyvinylpyrrolidone powders by micellar electrokinetic chromatography

- Successful separation of ɛ-caprolactam, melamine and urea deliberately added to povidone products by SDS-MEKC.
- The separations were performed in 50 mM phosphate buffer (pH 7.0) containing 2% (w/v) sodium dodecyl sulfate (SDS).
- The relative migration times (RMT) were found to be less than 0.15% for intra-day precision and less than 1.0% for inter-day precision.
- The detection limits were determined to be 11.5 μM, 3.5 μM and 0.4 mM for ɛ-caprolactam, melamine and urea, respectively.