| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7630971 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 8 Pages |
Abstract
- Simultaneous determination of ATRA and cholecalciferol (vitamin D3) using UPLC in rat plasma.
- Sensitive and reproducible method; low LOD of 0.5Â ng/ml
- Both ATRA and cholecalciferol are highly prone to degradation and were therefore incorporated into solid lipid nanoparticles (SLNs).
- Characterization of vitamins loaded SLNs.
- Pharmacokinetic studies after simultaneous subcutaneous administration as free solution or SLNs of both Vitamins, in rats.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Manoj Kumar, Gaurav Sharma, Dinesh Singla, Sukhjeet Singh, Sudhir Sahwney, Anurag S. Chauhan, Gagandeep Singh, Indu Pal Kaur,