Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7631131 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 5 Pages |
Abstract
- Chiral CE methods for (R)-MDL 100,907 and its key intermediate were developed.
- Carboxymethylated γ- and sulfobuthylated β-cyclodextrins were good selectors.
- pKa were calculated and analytes were separated in fully protonated state.
- Stabilities and mobilities of CD complexes were determined for method optimization.
- Method applicability was checked.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Krisztina Németh, Roberta Palkó, Péter Kovács, Júlia Visy,