| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631361 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 4 Pages |
Abstract
- New phase II metabolites were found during biotransformation of nabumetone in minipigs.
- The metabolites were identified by coupling HPLC/ESI-MS/MS.
- Phase I metabolites are subsequently conjugated with glucuronide acid and glycine.
- Metabolites were found in small intestine content, they were absent in minipig urine.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Lenka Äeslová, Michal HolÄapek, Milan Nobilis,