| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631375 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 34 Pages |
Abstract
- All the degradation products of tamsulosin were well resolved from parent drug as well as from each other in a gradient method.
- Identified 12 hitherto unknown degradation products formed under various stress degradation conditions.
- Structure elucidation of degradation products has been carried out using online LC-MS/MS experiments in combination with accurate mass measurements.
- Probable mechanisms are proposed for the formation of degradation products.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Deepak Namdev, Roshan M. Borkar, B. Raju, Pradipbhai D. Kalariya, Vinodkumar T. Rahangdale, S. Gananadhamu, R. Srinivas,