| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631376 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 6 Pages |
Abstract
- Reaction between PEG 400 and 2 APIs resulted in formation of PEG adducts.
- Separation of PEG adducts was performed with supercritical fluid chromatography.
- Cetirizine was more reactive towards PEG 400 than indomethacin.
- Detection with mass spectrometry is well-suited for identification of PEG adducts.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Anne Marie V. Schou-Pedersen, Jesper Ãstergaard, Mats Johansson, Stephane Dubant, Rune B. Frederiksen, Steen Honoré Hansen,