| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631467 | Journal of Pharmaceutical and Biomedical Analysis | 2014 | 7 Pages |
Abstract
- Retention constants, RM0 and C0 for new androstene derivatives were determined at RP- and NP-TLC.
- QSRR proved RM0 and C0 to account for lipophilicity of the analytes.
- Absorption, distribution and elimination (ADME) parameters were determined in silico.
- QSAR allowed prediction of ADME parameters of analytes in terms of RM0i.e. C0, the size and the polarity of the molecules.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
NataÅ¡a P. MiloÅ¡eviÄ, Srdjan Z. StojanoviÄ, Katarina Penov-GaÅ¡i, Nada PeriÅ¡iÄ-JanjiÄ, Roman Kaliszan,