| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631506 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 10 Pages |
Abstract
- Tacrolimus capsules from five sources have similar biological potencies.
- All tacrolimus products inhibit the calcineurin/IL-2 pathway with similar efficacies.
- Any ascomycin is below the detection limits of both NMR or LC-MS.
- No other literature predicted impurities were observed in the marketplace products.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Cynthia D. Sommers, Eric S. Pang, Houman Ghasriani, Robert T. Berendt, Vincent L. Vilker, David A. Keire, Michael T. II,