| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631653 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 34 Pages |
Abstract
- An UPLC-MS/MS method to quantify 3-hydroxyflavone and its glucuronide was developed.
- The sensitive method was applied for pharmacokinetic study.
- The sensitive method was applied for absorption and metabolism study.
- The metabolite of 3-hydroxyflavone was identified.
Keywords
UDPGACXPMPBHBSSMPALLOQUPLCKPI3-hydroxyflavoneAUCUPLC–MS/MSI.S.internal standardcollision energypotassium phosphate bufferAbsorptionlower limit of quantificationPharmacokineticsMetabolismHank's balanced salt solutionarea under the curvedeclustering potentialcollision cell exit potentialUltra-performance liquid chromatographyquality control
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Beibei Xu, Guanyi Yang, Shufan Ge, Taijun Yin, Ming Hu, Song Gao,