Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7631660 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 9 Pages |
Abstract
- LC-MS/MS methods for ten drug transporters (ABCB1, ABCC2, ABCC3, ABCG2, OATP1A2, OATP2B1, PEPT1, ASBT, OCT1 and OCT3).
- First quantitative assays for ABCC3, OATP1A2, PEPT1, ASBT, OCT1 and OCT3.
- Comprehensive method validation for all transporters.
- Application to analyze human intestinal transporter expression; first comprehensive human intestinal expression data.
- mRNA and protein expression data from human jejunum and ileum.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
C. Gröer, S. Brück, Y. Lai, A. Paulick, A. Busemann, C.D. Heidecke, W. Siegmund, S. Oswald,