Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7631781 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 9 Pages |
Abstract
- HPLC method for purity determination of temozolomide drug substance was developed.
- It is crucial to control stability of both temozolomide and its degradation product.
- We proposed a novel approach to analysis of substance which is unstable in solution.
- Mathematical correction eliminates the necessity to analyse freshly dissolved samples.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Åukasz Jedynak, Maria Puchalska, Marta Zezula, Marta Åaszcz, Wojciech Åuniewski, Joanna Zagrodzka,