Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7631801 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 7 Pages |
Abstract
- First study that systematically compared IAM/NEM in SDS-PAGE artifact inhibition.
- The artifact inhibition activity of both agents is concentration dependent.
- 5Â mM NEM achieves the same inhibition effect as 40Â mM IAM under same conditions.
- NEM retained activity after prolonged sample heating, whereas IAM did not.
- NEM has a better inhibition effect than IAM on all tested IgG4 proteins.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Zhiqing C. Zhu, Yingchen Chen, Michael S. Ackerman, Bei Wang, Wei Wu, Bo Li, Linda Obenauer-Kutner, Rulin Zhao, Li Tao, Peter M. Ihnat, Jinping Liu, Rajesh B. Gandhi, Bo Qiu,