Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7631825 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 6 Pages |
Abstract
- High-resolution RPLC is a valuable strategy for monoclonal antibody analysis.
- Long columns packed with sub-2 μm particles provide very high separation power.
- Adsorption of intact mAb at the surface of the stationary phase remained minimal.
- Peak capacities of >700 were achieved for digested mAb using 450Â mm long column.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Szabolcs Fekete, Michael W. Dong, Taylor Zhang, Davy Guillarme,