| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7631827 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 23 Pages |
Abstract
- The biorelevant solubility of compounds with different acid-base properties were measured using validated saturation shake-flask method.
- The precise evaluation of the ionization/solubilization effect on BRM solubility is done.
- The biorelevant solubility of ampholyte niflumic acid is explained with the microspeciation of the molecule.
- The relationship between the administration and the biorelevant solubility of drugs is discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Krisztina Takács-Novák, Vera SzÅke, Gergely Völgyi, Péter Horváth, Rita Ambrus, Piroska Szabó-Révész,