| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7632169 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 5 Pages |
Abstract
⺠A micromethod for measuring of propranolol on dried blood spot (DBS) is proposed. ⺠Propranolol on DBS was stable under all storage temperatures tested for at least one month. ⺠The plasma comparison with DBS showed a good correlation. ⺠Use of DBS offers a great advantage in sampling for pharmacokinetic studies from pediatric patients.
Keywords
DBSLLOQβ-ARsHCTROPMRMGC/MSLC–MS/MSRetinopathy of prematurityLLODMass spectrometrylower limit of detectionlower limit of quantitationmultiple reaction monitoringDried blood spothematocritPropranololLiquid chromatography/tandem mass spectrometryliquid chromatography–tandem mass spectrometryhigh-performance liquid chromatographyHPLCgas chromatography coupled with mass spectrometry
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Maria Luisa Della Bona, Sabrina Malvagia, Fabio Villanelli, Elisa Giocaliere, Daniela Ombrone, Silvia Funghini, Luca Filippi, Giacomo Cavallaro, Paola Bagnoli, Renzo Guerrini, Giancarlo la Marca,