Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7632202 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 5 Pages |
Abstract
⺠Mechanisms of ultrasound-mediated drug release from liposomes were investigated. ⺠The drug release mechanism was dependent on the liposome membrane composition. ⺠Liposomes based on the lipid DOPE were irreversible disrupted after US-release. ⺠Most of the HSPC-liposomes remained intact without entrapped drug after US-release. ⺠Distinctive release mechanism may explain differences in sonosensitive properties.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tove J. Evjen, Stefan Hupfeld, Sabine Barnert, Sigrid Fossheim, Rolf Schubert, Martin Brandl,