Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7632270 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 34 Pages |
Abstract
⺠Raman chemical imaging was enhanced by applying SERS colloid on the samples. ⺠Distribution of trace amount of API was revealed below Raman limit of detection. ⺠Asymmetric least squares, a new method was used for baseline correction. ⺠MCR-ALS is required to resolve and identify SERS spectra and to create images. ⺠Proposed method intended for comparison of unknown samples with trace amount of drug.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tamás Firkala, Attila Farkas, Balázs Vajna, István Farkas, György Marosi,