Article ID Journal Published Year Pages File Type
7632270 Journal of Pharmaceutical and Biomedical Analysis 2013 34 Pages PDF
Abstract
► Raman chemical imaging was enhanced by applying SERS colloid on the samples. ► Distribution of trace amount of API was revealed below Raman limit of detection. ► Asymmetric least squares, a new method was used for baseline correction. ► MCR-ALS is required to resolve and identify SERS spectra and to create images. ► Proposed method intended for comparison of unknown samples with trace amount of drug.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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