| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7632407 | Journal of Pharmaceutical and Biomedical Analysis | 2013 | 5 Pages |
Abstract
⺠The absolute bioavailability of a new oral topotecan formulation was estimated. ⺠The pharmacokinetics of oral topotecan in Chinese patients was first studied. ⺠A sensitive and time saving UPLC-MS/MS assay has been developed. ⺠The conversion between the lactone and carboxylate forms of topotecan was studied. ⺠The present study builds a bridge for further clinical research of oral topotecan.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Ning Li, Xiaohong Han, Jianliang Yang, Lin Gui, Yuanyuan Song, Ping Du, Yuankai Shi,