A validated GC-MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules

Article ID	Journal	Published Year	Pages	File Type
7632451	Journal of Pharmaceutical and Biomedical Analysis	2012	7 Pages	PDF

Abstract

âº A fast headspace-GC-MS method was developed for residual solvent analysis. âº The quantitative analysis was validated for 10 solvents applying the total error approach. âº All relative expanded uncertainties were around 5%. âº The method was applied for the analysis of relative solvents in counterfeit tablets and capsules.

Keywords

GC–MS Method validation Counterfeit Residual solvents headspace

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

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A validated GC-MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules

Authors

E. Deconinck, M. Canfyn, P.-Y. Sacré, S. Baudewyns, P. Courselle, J.O. De Beer,