| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7632469 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 7 Pages |
Abstract
Extracts produced using ethyl acetate, hexane-ethyl acetate (95:5, v/v), hexane and ethanol were examined in the study. Extended residue reconstitution times resulted in a significant increase in the number and concentration of impurities in the mobile phase, requiring the development of a new HPLC-UV analytical method to exact adequate separation of artemisinin for quantification. The solvent selectivity and capacity for each of the solvent extraction approaches was then determined using the new reconstitution and HPLC-UV methods.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Josh L. Pilkington, Chris Preston, Rachel L. Gomes,