Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7632551 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 14 Pages |
Abstract
⺠The stability of a new 4â²-azido-2â²-deoxy nucleoside analog was investigated. ⺠The azide moiety induced drug degradation upon exposure to light. ⺠Photolysis products were identified by LC-MS and NMR analysis. ⺠Three main photodegradation pathways were unraveled.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tom Huybrechts, Maurice Hermans, Bart Van Hoof, Guy Winderickx, Carla De Neef, Steven Hostyn, Sara Vrielynck, Wim Vermeulen,