Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7632745 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 7 Pages |
Abstract
An LC-MS/MS method was developed for unambiguous differentiation of r-metHu-Leptin from endogenous leptin in human plasma. Using this method, specific quantitative information was obtained for pharmacokinetic studies in a clinical trial. The method should prove useful in quantifying this investigational drug against endo-leptin background in future clinical studies.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yan Wang, Joseph S. Heilig,