Article ID Journal Published Year Pages File Type
7632745 Journal of Pharmaceutical and Biomedical Analysis 2012 7 Pages PDF
Abstract
An LC-MS/MS method was developed for unambiguous differentiation of r-metHu-Leptin from endogenous leptin in human plasma. Using this method, specific quantitative information was obtained for pharmacokinetic studies in a clinical trial. The method should prove useful in quantifying this investigational drug against endo-leptin background in future clinical studies.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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