| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7632816 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 5 Pages |
Abstract
⺠A new LC-ESI-ITMS method is established for the determination of PDE5 inhibitors. ⺠A sample treatment using HybridSPE-Precipitation cartridges is proposed. ⺠The method permits the determination of analytes in serum and brain tissue. ⺠The study has been the first to evaluate the rat brain levels of PDE5 inhibitors.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Nora Unceta, Leire Echeazarra, Mario Montaña, Joan Sallés, Alberto Gómez-Caballero, M. Aránzazu Goicolea, Ramón J. Barrio,