| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7633125 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 10 Pages |
Abstract
The overall injection interval was less than 5.5 min. Regression coefficients of the calibration curves and limits of quantification (LOQ) showed a good coverage of over-therapeutic, therapeutic and sub-therapeutic ranges. Recovery rates, measured as percentage of recovery of spiked plasma samples, were â¥94%. Precision and accuracy data have been satisfactory for a therapeutic drug monitoring (TDM) service as for managing plasma samples from patients receiving psycho-pharmacological treatment.
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Authors
Gennaro Vecchione, Bruno Casetta, Antonella Chiapparino, Alessandro Bertolino, Michela Tomaiuolo, Filomena Cappucci, Raffaella Gatta, Maurizio Margaglione, Elvira Grandone,