| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7633170 | Journal of Pharmaceutical and Biomedical Analysis | 2012 | 8 Pages |
Abstract
⺠The interaction between harmalol and human serum albumin has been investigated. ⺠The results obtained revealed that harmalol has moderate affinities for HSA and binds mainly to subdomain IIA. ⺠Hydrogen bonding formation and van der Waals forces play major role in the binding process. ⺠Excellent agreement was found between the experimental and theoretical results regarding the mechanism of binding and binding constants.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bahram Hemmateenejad, Mojtaba Shamsipur, Fayezeh Samari, Taghi Khayamian, Malihe Ebrahimi, Zahra Rezaei,