Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid screenings: A guide through bioinformatics tools

Article ID	Journal	Published Year	Pages	File Type
7633895	Journal of Proteomics	2018	51 Pages	PDF

Abstract

General workflow to explore yeast two-hybrid results using bioinformatics tools. Figures were produced using Servier Medical Art from www.servier.com.118

Keywords

PTM PPIN DNA Data Bank of Japan DDBJ EMBL RefSeq htt IPI APP CRM Y2H PPI PDB TSA STS NCBI WGS European Molecular Biology Laboratory Tissue expression Huntington disease Protein-protein interaction post-translational modifications Whole-genome sequencing Reference Sequence sequence-tagged site International Protein Index Protein-protein interaction network Protein-protein interaction networks Co-IP Phenotypes Cis-regulatory module yeast two-hybrid National Center for Biotechnology Information Pathways MIM Transcriptome shotgun assembly Mendelian Inheritance in Man Huntingtin Ontology Co-Immunoprecipitation polymerase chain reaction PCR Databases Protein Data Bank amyloid precursor protein Caspase-6

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

Adding biological meaning to human protein-protein interactions identified by yeast two-hybrid screenings: A guide through bioinformatics tools

Authors

Juliana Felgueiras, Joana Vieira Silva, Margarida Fardilha,